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    Kenneth A Alexander, MD

    Infectious Disease
    (407) 650-7715
    Researcher Profile

    Primary Office

    ²¨É«µ¥Ë« Hospital, Florida ²¨É«µ¥Ë« Hospital, Florida 6535 Nemours Parkway Orlando, FL 32827
    Appointment: (407) 650-7715

    Other Offices

    Get to Know Me

    My wife and I have two adult daughters, both of whom — like me — are outspoken on the subject of immunizations. They were among the first girls in Chicago to get the HPV (human papillomavirus) vaccine. One of our daughters now works in health policy research. We believe that immunizations are what we do to protect ourselves and each other.

    Why I Treat Children

    Like every pediatrician, I love children and want the best for them. I also enjoy being around other people who care for children. I have found that people in the pediatric field tend to value the same things — children, family and each other.

    What I'm Passionate About

    I’m very passionate about immunizing children against diseases. It is the single most beneficial thing pediatricians and health providers can do for a child’s health. One of my focus areas at Nemours is to promote school-located vaccination. I also helped create the Nemours International Adoption Medicine Program.

    How I Try to Make A Difference

    I work hard to educate the public about the importance of childhood immunizations. I educate doctors and parents here in the United States and I travel globally to educate people in other countries. I try to engage people around important issues in child health, particularly immunization, which is our best defense against so many serious diseases.

    Education & Training

    Fellowship

    • Pediatric Infectious Diseases - Duke University Medical Center, 1995

    Residency

    • Pediatrics - Boston Children's Hospital, 1992

    Medical/Dental School

    • M.D. - University of Washington, 1989
    • University of Washington, 1989

    Board Certifications

    • American Board of Pediatrics/Pediatric Infectious Diseases

    Awards & Recognition

    • 2016 Orlando Magazine Best Doctors 2016
    • 2015 Best Doctors in America

    • Sam Lawrence Katz, MD, Memorial Essay; Journal of the Pediatric Infectious Diseases Society; (2023).

    • CD24 Expression Dampens the Basal Antiviral State in Human Neuroblastoma Cells and Enhances Permissivity to Zika Virus Infection; Viruses; (2022).

    • Answers to common questions about COVID-19 vaccines in children with cancer; Pediatric Blood and Cancer; (2022).

    • Subsequent malignant neoplasms in the Childhood Cancer Survivor Study: Occurrence of cancer types in which human papillomavirus is an established etiologic risk factor; Cancer; (2022).

    • Use of community forums to increase knowledge of HPV and cervical cancer in African American communities; Journal of Community Health; (2019).

    • Zika virus as an oncolytic treatment of human neuroblastoma cells requires CD24; PLoS ONE; (2018).

    • Team approach: Pyomyositis; JBJS Reviews; (2017).

    • Common and frustrating patient management problems; Pediatric Annals; (2016).

    • Repeated Blood Cultures in Pediatric Febrile Neutropenia: Would Following the Guidelines Alter the Outcome?; Pediatric Blood and Cancer; (2016).

    • Should pediatric practices have policies to not care for children with vaccine-hesitant parents?; Pediatrics; (2016).

    • Taxi Drivers: A Target Population for the Prevention of Transmissible Disease?; Journal of Community Health; (2016).

    • Infectious diseases; Pediatric Annals; (2015).

    • Challenges to school-located vaccination: Lessons learned; Pediatrics; (2014).

    • Adolescent sexual activity and cancer risk: Physicians' duty to inform?; Current Medical Research and Opinion; (2014).

    • An unusual cause of respiratory distress in a 17-year-old boy; Pediatric Annals; (2014).

    • Neonate with respiratory distress and shock; NeoReviews; (2014).

    • Pneumonia With chest wall invasion in a school-aged child; Journal of the Pediatric Infectious Diseases Society; (2014).

    • Recommendations for a national agenda to substantially reduce cervical cancer; Cancer Causes and Control; (2013).

    • Oral cavity tumors in younger patients show a poor prognosis and do not contain viral RNA; Oral Oncology; (2013).

    • A school-located vaccination adolescent pilot initiative in Chicago: Lessons learned; Journal of the Pediatric Infectious Diseases Society; (2013).

    • Coagulase negative staphylococci in the neonatal intensive care unit: Are we any smarter?; NeoReviews; (2013).

    • Culture negative sepsis and systemic inflammatory response syndrome in neonates; NeoReviews; (2013).

    • Safety and immunogenicity of the quadrivalent HPV vaccine in female Systemic Lupus Erythematosus patients aged 12 to 26 years; Pediatric Rheumatology; (2013).

    • Antibiotic Therapy and Early Onset Sepsis; NeoReviews; (2012).

    • Antimicrobial therapy and late onset sepsis; NeoReviews; (2012).

    • Barriers to HPV immunization for African American adolescent females; Vaccine; (2012).

    • Future directions in the evaluation and management of neonatal sepsis; NeoReviews; (2012).

    • Rationale for Reducing the Spread of Human Papillomavirus in Adolescents: Strategies to Improve Outcomes (CME Multimedia Activity); Journal of Adolescent Health; (2012).

    • HPV—Beyond Cervical Cancer (Online Resource Center); American Journal of Medicine; (2012).

    • Native joint septic arthritis caused by clostridium difficile in an 11-year old with hemoglobin SS disease; Pediatric Infectious Disease Journal; (2009).

    • Paediatricians' attitudes and practices towards HPV vaccination; Acta Paediatrica, International Journal of Paediatrics; (2008).

    • Pediatricians are more supportive of the human papillomavirus vaccine than the general public; Southern Medical Journal; (2008).

    • Development and cardiac contractility: Cardiac troponin T isoforms and cytosolic calcium in rabbit; Pediatric Research; (2006).

    • High potency silencing by single-stranded boranophosphate siRNA; Nucleic Acids Research; (2006).

    • Diagnosis and management of human papillomavirus infections; Pediatric Infectious Disease Journal; (2005).

    • RNA interference using boranophosphate siRNAs: Structure-activity relationships; Nucleic Acids Research; (2004).

    • Trp<sup>2063</sup> and Trp<sup>2064</sup> in the Factor Va C2 Domain Are Required for High-Affinity Binding to Phospholipid Membranes but Not for Assembly of the Prothrombinase Complex; Biochemistry; (2004).

    • Identification of Peptides that Inhibit the DNA Binding, trans-Activator, and DNA Replication Functions of the Human Papillomavirus Type 11 E2 Protein; Journal of Virology; (2004).

    • RNA interference of human papillomavirus type 18 E6 and E7 induces senescence in HeLa cells; Journal of Virology; (2003).

    • Human TATA binding protein inhibits human papillomavirus type 11 DNA replication by antagonizing E1-E2 protein complex formation on the viral origin of replication; Journal of Virology; (2002).

    • Infections diagnosed in the first year after pediatric stem cell transplantation; Pediatric Infectious Disease Journal; (2002).

    • Mechanism of termination of DNA replication of Escherichia coli involves helicase-contrahelicase interaction; Proceedings of the National Academy of Sciences of the United States of America; (2001).

    • A Single Domain of the Replication Termination Protein of Bacillus subtilis Is Involved in Arresting both DnaB Helicase and RNA Polymerase; Journal of Biological Chemistry; (2001).

    • Bacteremia, central catheters, and neonates: When to pull the line; Pediatrics; (2001).

    • Recent advances in diagnosis and therapy of human papillomaviruses; Expert Opinion on Investigational Drugs; (2000).

    • The E1 helicase of human papillomavirus type 11 binds to the origin of replication with low sequence specificity; Virology; (2000).

    • Subunit affinities and stoichiometries of the human papillomavirus type II E1:E2:DNA complex; Biochemistry; (1999).

    • The MotA transcriptional activator of bacteriophage T4 binds to its specific DNA site as a monomer; Biochemistry; (1998).

    • A fluorescence anisotropy study of DNA binding by HPV-11 E2C protein: A hierarchy of E2-binding sites; Biochemistry; (1996).

    • Antiviral therapy for human papillomaviruses: Rationale and prospects; Annals of Internal Medicine; (1995).

    • Successful treatment of abdominal wall rhizopus necrotizing cellulitis in a preterm infant; Pediatric Infectious Disease Journal; (1995).

    • Fluorescence Energy Transfer Analysis of Calmodulin â‹…Peptide Complexes; Biochemistry; (1992).

    • Characterization of the calmodulin binding domain of neuromodulin. Functional significance of serine 41 and phenylalanine 42; Journal of Biological Chemistry; (1991).

    • Regulation of Free Calmodulin Levels in Neurons by Neuromodulin: Relationship to Neuronal Growth and Regeneration; Current Topics in Cellular Regulation; (1990).

    • Identification and characterization of the calmodulin-binding domain of neuromodulin, a neurospecific calmodulin-binding protein.; The Journal of biological chemistry; (1988).

    • Amino Acid Sequence of P-57, a Neurospecific Calmodulin-Binding Protein; Biochemistry; (1987).

    • Regulation of calmodulin binding to P-57. A neurospecific calmodulin binding protein.; Journal of Biological Chemistry; (1987).

    • Physicochemical and Hydrodynamic Characterization of P-57, a Neurospecific Calmodulin Binding Protein; Biochemistry; (1986).

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