Rodney Scott, MD
Division Chief Neurology-
Drug-resistant focal epilepsy in children is associated with increased modal controllability of the whole brain and epileptogenic regions; Communications Biology; (2022).
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MRI for assessing the impact of febrile status epilepticus and predicting outcomes; Febrile Seizures: New Concepts and Consequences; (2022).
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Seizure outcome determinants in children after surgery for single unilateral lesions on MRI : role of preoperative ictal and interictal EEG; Epilepsia; (2022).
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Expedited epilepsy surgery prior to drug resistance in children: a frontier worth crossing?; Brain; (2022).
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Biological networks and complexity in early-onset motor neuron diseases; Frontiers in Neurology; (2022).
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Mechanisms for Cognitive Impairment in Epilepsy: Moving Beyond Seizures; Frontiers in Neurology; (2022).
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Differential regulation of gene expression pathways with dexamethasone and ACTH after early life seizures; Unknown Source; (2022).
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Differential regulation of gene expression pathways with dexamethasone and ACTH after early life seizures; Neurobiology of Disease; (2022).
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Brains, complex systems and therapeutic opportunities in epilepsy; Seizure; (2021).
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The UK experience of stereoelectroencephalography in children: An analysis of factors predicting the identification of a seizure-onset zone and subsequent seizure freedom; Epilepsia; (2021).
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The UK experience of stereoelectroencephalography in children: An analysis of factors predicting the identification of a seizure onset zone and subsequent seizure freedom; medRxiv; (2021).
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Levetiracetam for treatment of convulsive status epilepticus: Time to update childhood convulsive status epilepticus treatment guidelines?; Archives of Disease in Childhood; (2021).
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Gregory L. Holmes; Child Neurology: Its Origins, Founders, Growth and Evolution; (2021).
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Fine Spike Timing in Hippocampal-Prefrontal Ensembles Predicts Poor Encoding and Underlies Behavioral Performance in Healthy and Malformed Brains; Cerebral Cortex; (2021).
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Drug-resistant focal epilepsy in children is associated with increased modal controllability of the whole brain and epileptogenic regions; medRxiv; (2021).
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Focal dorsal hippocampal nav1.1 knock down alters place cell temporal coordination and spatial behavior; Cerebral Cortex; (2020).
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Current understanding of febrile seizures and their long鈥恡erm outcomes; Developmental Medicine & Child Neurology; (2020).
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Subcortical nuclei volumes are associated with cognition in children post-convulsive status epilepticus: Results at nine years follow-up; Epilepsy and Behavior; (2020).
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Headache in children with Sturge-Weber syndrome - Prevalence, associations and impact; European Journal of Paediatric Neurology; (2020).
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Microelectrode recordings in human epilepsy: a case for clinical translation; Brain Communications; (2020).
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Intelligence and memory outcomes within 10鈥痽ears of childhood convulsive status epilepticus; Epilepsy and Behavior; (2019).
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Imaging Biomarkers for Febrile Status Epilepticus and Other Forms of Convulsive Status Epilepticus; Imaging Biomarkers in Epilepsy; (2019).
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Global development and adaptive behaviour in children with early-onset epilepsy: a population-based case鈥揷ontrol study; Developmental Medicine and Child Neurology; (2019).
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Experiences and needs of parents of young children with active epilepsy: A population-based study; Epilepsy and Behavior; (2019).
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Distributed dynamic coding for spatial working memory in hippocampal-prefrontal networks; bioRxiv; (2019).
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Autism, ADHD and parent-reported behavioural difficulties in young children with epilepsy; Seizure; (2019).
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Pathophysiology of convulsive status epilepticus; Seizure; (2019).
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Long-term outcomes after childhood convulsive status epilepticus; Current Opinion in Pediatrics; (2019).
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Symptoms of depression, anxiety, and stress in parents of young children with epilepsy: A case controlled population-based study; Epilepsy and Behavior; (2018).
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Parenting stress and perceived stigma in mothers of young children with epilepsy: A case鈥揷ontrol study; Epilepsy and Behavior; (2018).
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Long-term prognosis after childhood convulsive status epilepticus: a prospective cohort study; The Lancet Child and Adolescent Health; (2018).
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Long-term behavioural outcomes after paediatric convulsive status epilepticus: a population-based cohort study; Developmental Medicine and Child Neurology; (2018).
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Environmental enrichment normalizes hippocampal timing coding in a malformed hippocampus; PLOS ONE; (2018).
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WONOEP APPRAISAL: The many facets of epilepsy networks; Epilepsia; (2018).
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Cognitive outcomes following epilepsy in infancy: A longitudinal community鈥恇ased study; Epilepsia; (2018).
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Child and parental sleep in young children with epilepsy: A population鈥恇ased case鈥恈ontrol study; Epilepsia Open; (2018).
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Auditory processing following infantile spasms: An event-related potential study; Epilepsia; (2017).
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Parent- and Teacher-Reported Symptoms of ADHD in School-Aged Children With Active Epilepsy: A Population-Based Study; Journal of Attention Disorders; (2017).
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Methodological standards and functional correlates of depth in聽vivo electrophysiological recordings in control rodents. A TASK1-WG3 report of the AES/ILAE Translational Task Force of the ILAE; Epilepsia; (2017).
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Long-term white matter tract reorganization following prolonged febrile seizures; Epilepsia; (2017).
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Factors associated with reported challenging behavior in young people with epilepsy and neurodevelopmental problems: Data from a specialist epilepsy center; Epilepsia Open; (2017).
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Brain abnormalities in fetuses: in-utero MRI versus ultrasound; The Lancet; (2017).
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Environmental Enrichment Normalizes Hippocampal Timing Coding in a Malformed Hippocampus; bioRxiv; (2017).
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Epilepsy and autism spectrum disorders: Relatively related; Neurology; (2016).
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Efficacy of nonselective optogenetic control of the medial septum over hippocampal oscillations: The influence of speed and implications for cognitive enhancement; Physiological Reports; (2016).
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ACTH prevents deficits in fear extinction associated with early life seizures; Frontiers in Neurology; (2016).
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Network science for the identification of novel therapeutic targets in epilepsy [version 1; referees: 2 approved]; Unknown Source; (2016).
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Temporal Coordination of Hippocampal Neurons Reflects Cognitive Outcome Post-febrile Status Epilepticus; EBioMedicine; (2016).
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Oscillation phase locking and late ERP components of intracranial hippocampal recordings correlate to patient performance in a working memory task; Frontiers in Human Neuroscience; (2016).
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Short-range temporal interactions in sleep; Hippocampal spike avalanches support a large milieu of sequential activity including replay; PLoS ONE; (2016).
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Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures; Nature Communications; (2015).
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Mechanisms responsible for cognitive impairment in epileps; Cold Spring Harbor Perspectives in Medicine; (2015).
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Features of developmental coordination disorder in active childhood epilepsy: A population-based study; Developmental Medicine and Child Neurology; (2015).
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Features of autism spectrum disorder (ASD) in childhood epilepsy: A population-based study; Epilepsy and Behavior; (2015).
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Factors associated with quality of life in active childhood epilepsy: A population-based study; European Journal of Paediatric Neurology; (2015).
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Erratum: Status epilepticus induced spontaneous dentate gyrus spikes: In vivo current source density analysis (PLoS ONE (2015) 10:8 (e0136125) DOI: 10.1371/journal.pone.0136125); PLoS ONE; (2015).
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Cognition in school-aged children with "active" epilepsy: A population-based study; Journal of Clinical and Experimental Neuropsychology; (2015).
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Standard dose valproic acid does not cause additional cognitive impact in a rodent model of intractable epilepsy; Epilepsy Research; (2015).
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The health, education, and social care costs of school-aged children with active epilepsy: A population-based study; Epilepsia; (2015).
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Temporal lobe impairment in west syndrome: Event-related potential evidence; Annals of Neurology; (2015).
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T2 relaxation time post febrile status epilepticus predicts cognitive outcome; Experimental Neurology; (2015).
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Symptoms of anxiety and depression in school-aged children with active epilepsy: A population-based study; Epilepsy and Behavior; (2015).
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Status epilepticus induced spontaneous dentate gyrus spikes: In vivo current source density analysis; PLoS ONE; (2015).
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State-Dependent Differences in Functional Connectivity in Young Children With Autism Spectrum Disorder; EBioMedicine; (2015).
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Quantitative magnetic resonance imaging evidence for altered structural remodeling of the temporal lobe in West syndrome; Epilepsia; (2015).
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Attention deficit associated with early life interictal spikes in a rat model is improved with ACTH; PLoS ONE; (2014).
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A comparison of continuous video-EEG monitoring and 30-minute EEG in an ICU; Epileptic Disorders; (2014).
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What are the effects of prolonged seizures in the brain?; Epileptic Disorders; (2014).
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Screening for mental health disorders in active childhood epilepsy: Population-based data; Epilepsy Research; (2014).
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Neurobehavioral comorbidities in children with active epilepsy: A population-based study; Pediatrics; (2014).
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Hippocampal sclerosis and other forms of status epilepticus; Annals of Neurology; (2014).
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Focal epileptiform activity in the prefrontal cortex is associated with long-term attention and sociability deficits; Neurobiology of Disease; (2014).
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Dexamethasone exacerbates cerebral edema and brain injury following lithium-pilocarpine induced status epilepticus; Neurobiology of Disease; (2014).
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Academic achievement in school-aged children with active epilepsy: A population-based study; Epilepsia; (2014).
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Cognitive impairment in temporal lobe epilepsy: Role of online and offline processing of single cell information; Hippocampus; (2014).
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Consequences of febrile seizures in childhood; Current Opinion in Pediatrics; (2014).
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A population-based study of newly diagnosed epilepsy in infants; Epilepsia; (2013).
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Diagnosis of probable psychogenic nonepileptic seizures in the outpatient clinic: Does gender matter?; Epilepsy and Behavior; (2013).
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Methylphenidate treatment of attention deficit hyperactivity disorder in young people with learning disability and difficult-to-treat epilepsy: Evidence of clinical benefit; Epilepsia; (2013).
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Long-term seizure, cognitive, and psychiatric outcome following trans-middle temporal gyrus amygdalohippocampectomy and standard temporal lobectomy: Clinical article; Journal of Neurosurgery; (2013).
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Hippocampal volume loss following childhood convulsive status epilepticus is not limited to prolonged febrile seizures; Epilepsia; (2013).
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Hippocampal interictal epileptiform activity disrupts cognition in humans; Neurology; (2013).
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Focal Scn1a knockdown induces cognitive impairment without seizures; Neurobiology of Disease; (2013).
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Enrichment and training improve cognition in rats with cortical malformations; PLoS ONE; (2013).
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Early developmental outcomes in children following convulsive status epilepticus: A longitudinal study; Epilepsia; (2013).
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Altered short-term plasticity in the prefrontal cortex after early life seizures; Neurobiology of Disease; (2013).
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Prolonged febrile seizures cause reversible reductions in white matter integrity; NeuroImage: Clinical; (2013).
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Speed modulation of hippocampal theta frequency correlates with spatial memory performance; Hippocampus; (2013).
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Short duration waveforms recorded extracellularly from freely moving rats are representative of axonal activity; Frontiers in neural circuits; (2013).
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Before Epilepsy Unfolds: Opening up the potassium door in neonatal seizures; Nature Medicine; (2012).
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Outcome of frontal lobe epilepsy surgery; Epilepsia; (2012).
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Maturation of EEG oscillations in children with sodium channel mutations; Brain and Development; (2012).
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Lack of efficacy of phenytoin in children presenting with febrile status epilepticus; American Journal of Emergency Medicine; (2012).
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Joint time-frequency analysis of EEG signals based on a phase-space interpretation of the recording process; Proceedings of SPIE - The International Society for Optical Engineering; (2012).
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Imaging seizure-induced inflammation using an antibody targeted iron oxide contrast agent; NeuroImage; (2012).
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Functional network changes in hippocampal CA1 after status epilepticus predict spatial memory deficits in rats; Journal of Neuroscience; (2012).
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Febrile seizures and the wandering granule cell; Nature Medicine; (2012).
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Psychopathology in children before and after surgery for extratemporal lobe epilepsy; Developmental Medicine and Child Neurology; (2012).
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The role of magnetic resonance imaging in the follow-up of children with convulsive status epilepticus; Developmental Medicine and Child Neurology; (2012).
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Seizure prognosis of patients with low-grade tumors; Seizure; (2012).
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Seizure outcome after extratemporal epilepsy surgery in childhood; Developmental Medicine and Child Neurology; (2012).
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SCN1A mutations in Dravet syndrome: Impact of interneuron dysfunction on neural networks and cognitive outcome; Epilepsy and Behavior; (2012).
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Recognition memory is impaired in children after prolonged febrile seizures; Brain; (2012).
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Prediction of seizure outcome in childhood epilepsies in countries with limited resources: A prospective study; Developmental Medicine and Child Neurology; (2012).
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Early-life seizures produce lasting alterations in the structure and function of the prefrontal cortex; Epilepsy and Behavior; (2011).
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Cognitive outcome after extratemporal epilepsy surgery in childhood; Epilepsia; (2011).
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Causes of status epilepticus in children; The Causes of Epilepsy: Common and Uncommon Causes in Adults and Children; (2011).
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Death within 8 years after childhood convulsive status epilepticus: A population-based study; Brain; (2011).
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Enhanced oscillatory activity in the hippocampal-prefrontal network is related to short-term memory function after early-life seizures; Journal of Neuroscience; (2011).
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Maturational dynamics of hippocampal place cells in immature rats; Hippocampus; (2011).
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Impaired cognition in rats with cortical dysplasia: Additional impact of early-life seizures; Brain; (2011).
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Epilepsy surgery in children under 3 years; Epilepsy Research; (2011).
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Seizure outcome in infantile spasms-A retrospective study; Epilepsia; (2011).
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Outcomes of childhood epilepsy at age 33 years: A population-based birth-cohort study; Epilepsia; (2011).
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Cerebral blood flow changes during pilocarpine-induced status epilepticus activity in the rat hippocampus; Experimental Neurology; (2010).
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Adverse outcomes following convulsive status epilepticus in children: Relationship with hippocampal injury; Epilepsia; (2010).
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Statistical Process Control (SPC)-A simple objective method for monitoring seizure frequency and evaluating effectiveness of drug interventions in refractory childhood epilepsy; Epilepsy Research; (2010).
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Hippocampal interictal spikes disrupt cognition in rats; Annals of Neurology; (2010).
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Cognitive and behavioral comorbidities of epilepsy; Epilepsia; (2010).
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Quantitative MRI predicts status epilepticus-induced hippocampal injury in the lithium-pilocarpine rat model; Epilepsy Research; (2010).
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The effects of epilepsy surgery on emotions, behavior, and psychosocial impairment in children and adolescents with drug-resistant epilepsy: A prospective study; Epilepsy and Behavior; (2009).
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Status epilepticus in the developing brain: Long-term effects seen in humans; Epilepsia; (2009).
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Socioeconomic deprivation independent of ethnicity increases status epilepticus risk; Epilepsia; (2009).
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Phenomenology of prolonged febrile seizures: Results of the febstat study; Neurology; (2009).
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Management of convulsive status epilepticus in children; Archives of Disease in Childhood: Education and Practice Edition; (2009).
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Impaired everyday memory associated with encephalopathy of severe malaria: The role of seizures and hippocampal damage; Malaria Journal; (2009).
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Treatment of community-onset childhood convulsive status epilepticus - Authors' reply; The Lancet Neurology; (2009).
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Treatment of community-onset, childhood convulsive status epilepticus: a prospective, population-based study; The Lancet Neurology; (2008).
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The medical management of the epilepsies in children: conceptual and practical considerations; The Lancet Neurology; (2008).
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Is streamlined evaluation of children for epilepsy surgery possible?; Epilepsia; (2008).
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The epidemiology of convulsive status epilepticus in children: A critical review; Epilepsia; (2007).
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Proteome changes associated with hippocampal MRI abnormalities in the lithium pilocarpine-induced model of convulsive status epilepticus; Proteomics; (2007).
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Outcome of convulsive status epilepticus: A review; Archives of Disease in Childhood; (2007).
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Clinical update: childhood convulsive status epilepticus; Lancet; (2007).
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Clinical trial design in status epilepticus: Problems and solutions; Epilepsia; (2007).
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Childhood convulsive status epilepticus: Epidemiology, management and outcome; Acta Neurologica Scandinavica; (2007).
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Autonomic status epilepticus in panayiotopoulos syndrome and other childhood and adult epilepsies: A consensus view; Epilepsia; (2007).
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'Severe memory impairment in a child with bihippocampal injury after status epilepticus' [3]; Developmental Medicine and Child Neurology; (2007).
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Prolonged febrile seizures are associated with hippocampal vasogenic edema and developmental changes; Epilepsia; (2006).
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Outcome of paediatric convulsive status epilepticus: a systematic review; Lancet Neurology; (2006).
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Incidence, cause, and short-term outcome of convulsive status epilepticus in childhood: prospective population-based study; Lancet; (2006).
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Hippocampal sclerosis in children with lesional epilepsy is influenced by age at seizure onset; Epilepsia; (2006).
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Cognitive competence at the onset of West syndrome [1]; Developmental Medicine and Child Neurology; (2006).
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Childhood convulsive status epilepticus - Authors' reply; Lancet; (2006).
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Nonconvulsive status epilepticus: Epilepsy Research Foundation Workshop Reports; Epileptic Disorders; (2005).
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Meningitis is a common cause of convulsive status epilepticus with fever; Archives of Disease in Childhood; (2005).
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Buccal midazolam as rescue therapy for acute seizures; Lancet Neurology; (2005).
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A systematic review of the epidemiology of status epilepticus; European Journal of Neurology; (2004).
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Inappropriate emergency management of status epilepticus in children contributes to need for intensive care; Journal of Neurology, Neurosurgery and Psychiatry; (2004).
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The acute management of seizures in childhood; Hospital Medicine; (2004).
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Abnormalities in hippocampi remote from the seizure focus: A T<sub>2</sub> relaxometry study; Brain; (2003).
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Hippocampal abnormalities after prolonged febrile convulsion: A longitudinal MRI study; Brain; (2003).
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Magnetic resonance imaging findings within 5 days of status epilepticus in childhood; Brain; (2002).
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Erratum: Magnetic resonance imaging findings within 5 days of status epilepticus in childhood (Brain (2002) 125:9(1951-1959); Brain; (2002).
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Convulsive status epilepticus in children with intractable epilepsy is frequently focal in origin; Canadian Journal of Neurological Sciences; (2002).
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Quantitative magnetic resonance characterization of mesial temporal sclerosis in childhood; Neurology; (2001).
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Intranasal midazolam for treating febrile seizures in children [5] (multiple letters); British Medical Journal; (2001).
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Intranasal midazolam for treating febrile seizures in children; BMJ; (2001).
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Buccal midazolam may be a useful alternative to rectal diazepam for treating acute seizures in refractory epilepsy: Commentary; Evidence-Based Medicine; (2000).
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The treatment of convulsive status epilepticus in children; Archives of Disease in Childhood; (2000).
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Pharmacological management of convulsive status epilepticus in children; Developmental Medicine and Child Neurology; (1999).
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Buccal midazolam and rectal diazepam for treatment of prolonged seizures in childhood and adolescence: A randomised trial; Lancet; (1999).
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Buccal midazolam and rectal diazepam for epilepsy (multiple letters) [2]; Lancet; (1999).
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Status epilepticus: Pathophysiology, epidemiology, and outcomes; Archives of Disease in Childhood; (1998).
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Developmental perspectives on epilepsy; Current Opinion in Neurology; (1998).
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Buccal absorption of midazolam: Pharmacokinetics and EEG pharmacodynamics; Epilepsia; (1998).
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'Nasal rather than rectal benzodiazepines in the management of acute childhood seizures?' [1]; Developmental Medicine and Child Neurology; (1997).